Maternal Cryptosporidium Infection: A Neglected Infection in Makurdi Township, Benue State, Nigeria.Name : Dr. Emmanuel Msugh Mbaawuaga
Affliation : Deputy Director
University : Benue State University Makurdi
Country : Nigeria
Maternal Cryptosporidium infection is a neglected infection in Makurdi; an area with higher HIV rate in Nigeria, but the infection is suspected of contributing to childhood diarrhoea-related mortality. To assess Cryptosporidium infection, 255 feacal samples were randomly collected from volunteered consented antenatal attendees in Makurdi Township. The stool samples were concentrated using formol-ether oocyst concentration technique, stained with modified Ziehl Neelson cold stain and oocysts identified by microscopy. HIV sero-status was determined using Determine (Inverness, Japan) and confirmed with Uni-Gold HIV1/2 (Trinity Biotech, USA). Chi square (χ2) in an SPSS (version 20.0) software was used to compare categorical variables and significant association was determined at 95% level of probability. Cryptosporidium oocyst was identified in 49(19.2%) of the faecal samples examined. HIV positive attendees were more likely than HIV negative to be infected by Cryptosporium (84.4% vs 9.9%, P=0.000). We found a strong association between stool consistency (P=0.000), duration of diarrhoea (P=0.000), possession of domestic animals (P=0.000) and the infection rate. There was also a significant difference (P=0.014) between the rate of infection and sources of drinking water. However, infection could not be associated with age (P=0.348), type of toilet system in use (P=0.890) and literacy (P=0.853). Pregnant women in this study suffer a high burden of Cryptosporidium infection which could complicate HIV status of those immunocompromised culminating into diarrhoea-related mortality. Hence, minimizing the environmental burden and maternal Cryptosporidium infection could also protect against early infant infection reported in this setting.
Dr Emmanuel Msugh Mbaawuaga Completed His Ph.D (Medical Microbiology) From University Of Nigeria, Nsukka In 2015. He Is The Deputy Director Of Centre For Research Management, Benue State University Makurdi, Nigeria. He Has Won A Research Grant Of The Tertiary Education Trust Fund (TETFund) Nigeria, 2017. Dr Mbaawuaga Has Published Over 20 Papers In Reputable Journals And Has Reviewed Several Articles For A Number Of Journals.